Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM477066'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM477066 (US10882859, Example 1) Show SMILES CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CN(CCc2[nH]1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H27FN6O3/c1-2-15-12-23(34)19(27)13-18(15)16-3-4-17-21(11-16)30-31-24(17)25-28-20-5-6-33(14-22(20)29-25)26(35)32-7-9-36-10-8-32/h3-4,11-13,34H,2,5-10,14H2,1H3,(H,28,29)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.0520	n/a	n/a	n/a	n/a	n/a
TOPIVERT PHARMA LIMITED US Patent					Assay Description The biochemical JAK family enzyme binding assays carried out at DiscoveRx.				US Patent US10882859 (2021) BindingDB Entry DOI: 10.7270/Q2NZ8BQR
					More data for this Ligand-Target Pair