Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50311636'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50311636 (9-(tetrahydro-2H-pyran-4-yl)-2-(5-(trifluoromethyl...) Show SMILES FC(F)(F)c1ccc2n(cnc2c1)-c1ncc2[nH]c(=O)n(C3CCOCC3)c2n1 Show InChI InChI=1S/C18H15F3N6O2/c19-18(20,21)10-1-2-14-12(7-10)23-9-26(14)16-22-8-13-15(25-16)27(17(28)24-13)11-3-5-29-6-4-11/h1-2,7-9,11H,3-6H2,(H,24,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of human JAK2 (532-1132) by time resolved fluorescence assay				Bioorg Med Chem Lett 19: 6788-92 (2009) Article DOI: 10.1016/j.bmcl.2009.09.080 BindingDB Entry DOI: 10.7270/Q24B31G4
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