Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50337340'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50337340 ((2-bromophenyl)(4-(4-(5-methyl-1H-pyrazol-3-ylamin...) Show SMILES Cc1cc(Nc2nc(nn3cccc23)N2CCN(CC2)C(=O)c2ccccc2Br)[nH]n1 Show InChI InChI=1S/C21H21BrN8O/c1-14-13-18(26-25-14)23-19-17-7-4-8-30(17)27-21(24-19)29-11-9-28(10-12-29)20(31)15-5-2-3-6-16(15)22/h2-8,13H,9-12H2,1H3,(H2,23,24,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of JAK2 after 60 mins				Bioorg Med Chem Lett 21: 1425-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.022 BindingDB Entry DOI: 10.7270/Q2MG7PRT
					More data for this Ligand-Target Pair