Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50361220'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50361220 (CHEMBL1934349) Show SMILES CN(C)Cc1ccc(cc1)-c1ccc2cnc(Nc3ccc(cc3)C3CCN(CC(N)=O)CC3)nn12 Show InChI InChI=1S/C28H33N7O/c1-33(2)18-20-3-5-23(6-4-20)26-12-11-25-17-30-28(32-35(25)26)31-24-9-7-21(8-10-24)22-13-15-34(16-14-22)19-27(29)36/h3-12,17,22H,13-16,18-19H2,1-2H3,(H2,29,36)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assay				Bioorg Med Chem Lett 22: 133-7 (2011) Article DOI: 10.1016/j.bmcl.2011.11.049 BindingDB Entry DOI: 10.7270/Q2C829R4
					More data for this Ligand-Target Pair