Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50363233'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50363233 (CHEMBL1945707) Show SMILES CN1C\C=C\CCOc2cccc(c2)-c2ccnc(Nc3ccc(OCCN4CCCCC4)c(C1)c3)n2 |t:3| Show InChI InChI=1S/C30H37N5O2/c1-34-15-4-3-7-19-36-27-10-8-9-24(22-27)28-13-14-31-30(33-28)32-26-11-12-29(25(21-26)23-34)37-20-18-35-16-5-2-6-17-35/h3-4,8-14,21-22H,2,5-7,15-20,23H2,1H3,(H,31,32,33)/b4-3+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
S BIO Pte. Ltd. Curated by ChEMBL					Assay Description Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assay				J Med Chem 55: 169-96 (2012) Checked by Author Article DOI: 10.1021/jm201112g BindingDB Entry DOI: 10.7270/Q2M61KPN
					More data for this Ligand-Target Pair