Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50400318'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50400318 (CHEMBL2181085) Show SMILES Nc1cc2COCC=CCOCc3cccc(c3)-c3ccnc(Nc(c1)c2)n3 |w:8.8| Show InChI InChI=1S/C22H22N4O2/c23-19-11-17-12-20(13-19)25-22-24-7-6-21(26-22)18-5-3-4-16(10-18)14-27-8-1-2-9-28-15-17/h1-7,10-13H,8-9,14-15,23H2,(H,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
S*BIO Pte. Ltd. Curated by ChEMBL					Assay Description Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assay				J Med Chem 54: 4638-58 (2011) Article DOI: 10.1021/jm200326p BindingDB Entry DOI: 10.7270/Q2J1049M
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