Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM99710'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM99710 (US8501936, 212) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1cc(Nc2nc3c(cccn3n2)-c2ccc(cc2)S(C)(=O)=O)cn1 Show InChI InChI=1S/C26H31N7O4S/c1-26(2,3)37-25(34)31-14-11-20(12-15-31)33-17-19(16-27-33)28-24-29-23-22(6-5-13-32(23)30-24)18-7-9-21(10-8-18)38(4,35)36/h5-10,13,16-17,20H,11-12,14-15H2,1-4H3,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. US Patent					Assay Description The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...				US Patent US8501936 (2013) BindingDB Entry DOI: 10.7270/Q22Z1455
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