Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM109933'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM109933 (US8609647, 80) Show SMILES CC(C)(C)OC(=O)N1CCCCC11CCN(C1)c1ncnc2[nH]ccc12 Show InChI InChI=1S/C19H27N5O2/c1-18(2,3)26-17(25)24-10-5-4-7-19(24)8-11-23(12-19)16-14-6-9-20-15(14)21-13-22-16/h6,9,13H,4-5,7-8,10-12H2,1-3H3,(H,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Japan Tobacco Inc. US Patent					Assay Description In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...				US Patent US8609647 (2013) BindingDB Entry DOI: 10.7270/Q29C6W24
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