Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM139692'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM139692 (US8895544, 2 | US8895544, 3) Show SMILES CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CN(CCc2[nH]1)C(=O)c1ccsn1 Show InChI InChI=1S/C25H21FN6O2S/c1-2-13-10-22(33)17(26)11-16(13)14-3-4-15-20(9-14)29-30-23(15)24-27-18-5-7-32(12-21(18)28-24)25(34)19-6-8-35-31-19/h3-4,6,8-11,33H,2,5,7,12H2,1H3,(H,27,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.5	25
Pfizer Limited US Patent					Assay Description JAK3 enzyme (Invitrogen) stock solution is made up at 4.1 uM in sterile water. JAK3 enzyme stock is diluted to 2 nM in assay buffer (10 mM HEPES free...				US Patent US8895544 (2014) BindingDB Entry DOI: 10.7270/Q2S46QNM
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM139692 (US8895544, 2 | US8895544, 3) Show SMILES CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CN(CCc2[nH]1)C(=O)c1ccsn1 Show InChI InChI=1S/C25H21FN6O2S/c1-2-13-10-22(33)17(26)11-16(13)14-3-4-15-20(9-14)29-30-23(15)24-27-18-5-7-32(12-21(18)28-24)25(34)19-6-8-35-31-19/h3-4,6,8-11,33H,2,5,7,12H2,1H3,(H,27,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	25
Pfizer Limited US Patent					Assay Description JAK3 enzyme (Invitrogen) stock solution is made up at 4.1 uM in sterile water. JAK3 enzyme stock is diluted to 2 nM in assay buffer (10 mM HEPES free...				US Patent US8895544 (2014) BindingDB Entry DOI: 10.7270/Q2S46QNM
					More data for this Ligand-Target Pair