Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM350321 ((S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)isoquinol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Jak3 | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01026 BindingDB Entry DOI: 10.7270/Q2JM2FHN | |||||||||||
More data for this Ligand-Target Pair |