Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50121380'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50121380 (CHEMBL3622133) Show SMILES CCn1c(cc2c1nc(NC(=O)NCCOC)c1ncn(C)c21)C(=O)N(C1CC1)C1CC1 Show InChI InChI=1S/C22H29N7O3/c1-4-28-16(21(30)29(13-5-6-13)14-7-8-14)11-15-18-17(24-12-27(18)2)19(25-20(15)28)26-22(31)23-9-10-32-3/h11-14H,4-10H2,1-3H3,(H2,23,25,26,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assay				ACS Med Chem Lett 6: 845-9 (2015) Article DOI: 10.1021/acsmedchemlett.5b00225 BindingDB Entry DOI: 10.7270/Q2Q2421M
					More data for this Ligand-Target Pair