Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50311005'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50311005 (CHEMBL1078688 | N-(4-(2-(3-((4-hydroxypiperidin-1-...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1ccnc(Nc2cccc(CN3CCC(O)CC3)c2)n1 Show InChI InChI=1S/C23H27N5O3S/c1-32(30,31)27-19-7-5-18(6-8-19)22-9-12-24-23(26-22)25-20-4-2-3-17(15-20)16-28-13-10-21(29)11-14-28/h2-9,12,15,21,27,29H,10-11,13-14,16H2,1H3,(H,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	636	n/a	n/a	n/a	n/a	n/a	n/a
Cytopia Research Pty Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged JAK3 kinase				Bioorg Med Chem Lett 19: 5887-92 (2009) Article DOI: 10.1016/j.bmcl.2009.08.071 BindingDB Entry DOI: 10.7270/Q2C24WKM
					More data for this Ligand-Target Pair