Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50311025'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50311025 (CHEMBL1078720 | N-(cyanomethyl)-4-(2-(4-(3-(diethy...) Show SMILES CCN(CC)CCCOc1ccc(Nc2nccc(n2)-c2ccc(cc2)C(=O)NCC#N)cc1 Show InChI InChI=1S/C26H30N6O2/c1-3-32(4-2)18-5-19-34-23-12-10-22(11-13-23)30-26-29-16-14-24(31-26)20-6-8-21(9-7-20)25(33)28-17-15-27/h6-14,16H,3-5,17-19H2,1-2H3,(H,28,33)(H,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	362	n/a	n/a	n/a	n/a	n/a	n/a
Cytopia Research Pty Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged JAK3 kinase				Bioorg Med Chem Lett 19: 5887-92 (2009) Article DOI: 10.1016/j.bmcl.2009.08.071 BindingDB Entry DOI: 10.7270/Q2C24WKM
					More data for this Ligand-Target Pair