Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50011458'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50011458 (2-(4-Hydroxy-phenyl)-4-oxo-4H-chromene-3-carboxyli...) Show SMILES OC(=O)c1c(oc2ccccc2c1=O)-c1ccc(O)cc1 Show InChI InChI=1S/C16H10O5/c17-10-7-5-9(6-8-10)15-13(16(19)20)14(18)11-3-1-2-4-12(11)21-15/h1-8,17H,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+6	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.				J Med Chem 34: 798-806 (1991) BindingDB Entry DOI: 10.7270/Q2CF9P3J
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