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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50074247'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50074247
PNG
(CHEMBL350710 | Phosphoric acid mono-[4-((S)-2-acet...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N[C@@H](C)c1ccc(cc1)C(C)C
Show InChI InChI=1S/C28H40N3O7P/c1-17(2)15-25(27(33)29-19(5)23-11-9-22(10-12-23)18(3)4)31-28(34)26(30-20(6)32)16-21-7-13-24(14-8-21)38-39(35,36)37/h7-14,17-19,25-26H,15-16H2,1-6H3,(H,29,33)(H,30,32)(H,31,34)(H2,35,36,37)/t19-,25-,26-/m0/s1
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Similars
Article
PubMed
n/an/an/a 200n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity of the compound against p56 Lck tyrosine kinase SH2 domain was measured using glutathione S-transferase (GST) fusion protein

J Med Chem 42: 722-9 (1999)


Article DOI: 10.1021/jm980612i
BindingDB Entry DOI: 10.7270/Q2Q23ZDX
More data for this
Ligand-Target Pair