Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50077207'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50077207 ((S)-4-(4-Methoxy-benzylcarbamoyl)-4-{(S)-3-[4-(oxa...) Show SMILES COc1ccc(CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(NC(=O)C(O)=O)cc2)NC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C32H34N4O9/c1-45-24-13-9-22(10-14-24)19-33-29(40)25(15-16-28(38)39)36-30(41)26(35-27(37)18-20-5-3-2-4-6-20)17-21-7-11-23(12-8-21)34-31(42)32(43)44/h2-14,25-26H,15-19H2,1H3,(H,33,40)(H,34,42)(H,35,37)(H,36,41)(H,38,39)(H,43,44)/t25-,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assay				J Med Chem 42: 1757-66 (1999) Article DOI: 10.1021/jm980676t BindingDB Entry DOI: 10.7270/Q29P32BR
					More data for this Ligand-Target Pair