Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50101672'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50101672 (CHEMBL312396 | {4-[2-[1-(4-Methoxy-benzyl)-2-oxo-2...) Show SMILES COc1ccc(Cn2cccc(NC(=O)C(Cc3ccc(CC(O)=O)cc3)NC(=O)Cc3cccc4ccccc34)c2=O)cc1 Show InChI InChI=1S/C36H33N3O6/c1-45-29-17-15-26(16-18-29)23-39-19-5-10-31(36(39)44)38-35(43)32(20-24-11-13-25(14-12-24)21-34(41)42)37-33(40)22-28-8-4-7-27-6-2-3-9-30(27)28/h2-19,32H,20-23H2,1H3,(H,37,40)(H,38,43)(H,41,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd. Curated by ChEMBL					Assay Description Binding affinity for p56lck SH2 domain site				J Med Chem 44: 2421-31 (2001) BindingDB Entry DOI: 10.7270/Q26T0NB3
					More data for this Ligand-Target Pair