Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50301598'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50301598 (3-(1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidin-2-ylam...) Show SMILES CC(Nc1nccc(n1)-n1cnc2ccccc12)C1CN(CCN1C)C(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C29H30N8O/c1-20(32-28-30-14-13-27(34-28)37-19-31-24-9-5-6-10-25(24)37)26-18-36(16-15-35(26)2)29(38)33-23-12-11-21-7-3-4-8-22(21)17-23/h3-14,17,19-20,26H,15-16,18H2,1-2H3,(H,33,38)(H,30,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	75.2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Lck				Bioorg Med Chem Lett 19: 5440-3 (2009) Article DOI: 10.1016/j.bmcl.2009.07.102 BindingDB Entry DOI: 10.7270/Q2GX4BM0
					More data for this Ligand-Target Pair