Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50320208'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50320208 (1-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...) Show SMILES CN1CCN(CC1)c1ccc(cc1)-c1cnn2c(N)c(cnc12)-c1ccc(NC(=O)Nc2ccccc2Cl)cc1 Show InChI InChI=1S/C30H29ClN8O/c1-37-14-16-38(17-15-37)23-12-8-21(9-13-23)25-19-34-39-28(32)24(18-33-29(25)39)20-6-10-22(11-7-20)35-30(40)36-27-5-3-2-4-26(27)31/h2-13,18-19H,14-17,32H2,1H3,(H2,35,36,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute of Biomedical Research Curated by ChEMBL					Assay Description Inhibition of LCK				Bioorg Med Chem Lett 20: 3628-31 (2010) Article DOI: 10.1016/j.bmcl.2010.04.112 BindingDB Entry DOI: 10.7270/Q2XP754D
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50320208 (1-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...) Show SMILES CN1CCN(CC1)c1ccc(cc1)-c1cnn2c(N)c(cnc12)-c1ccc(NC(=O)Nc2ccccc2Cl)cc1 Show InChI InChI=1S/C30H29ClN8O/c1-37-14-16-38(17-15-37)23-12-8-21(9-13-23)25-19-34-39-28(32)24(18-33-29(25)39)20-6-10-22(11-7-20)35-30(40)36-27-5-3-2-4-26(27)31/h2-13,18-19H,14-17,32H2,1H3,(H2,35,36,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute of Biomedical Research Curated by ChEMBL					Assay Description Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assay				Bioorg Med Chem Lett 20: 3628-31 (2010) Article DOI: 10.1016/j.bmcl.2010.04.112 BindingDB Entry DOI: 10.7270/Q2XP754D
					More data for this Ligand-Target Pair