Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Mer (Homo sapiens (Human)) | BDBM246852 (((2R,5S)-5-{2-[(1R)- 1-hydroxyethyl]-1H- imidazo[4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | 25 |
Incyte Corporation US Patent | Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ... | US Patent US9708333 (2017) BindingDB Entry DOI: 10.7270/Q2KD20XW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Mer (Homo sapiens (Human)) | BDBM246852 (((2R,5S)-5-{2-[(1R)- 1-hydroxyethyl]-1H- imidazo[4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | 25 |
Incyte Corporation US Patent | Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ... | US Patent US9708333 (2017) BindingDB Entry DOI: 10.7270/Q2KD20XW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Mer (Homo sapiens (Human)) | BDBM246852 (((2R,5S)-5-{2-[(1R)- 1-hydroxyethyl]-1H- imidazo[4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <500 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation US Patent | Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ... | US Patent US10519163 (2019) BindingDB Entry DOI: 10.7270/Q28K7CGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Mer (Homo sapiens (Human)) | BDBM246852 (((2R,5S)-5-{2-[(1R)- 1-hydroxyethyl]-1H- imidazo[4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RJ4NMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Mer (Homo sapiens (Human)) | BDBM246852 (((2R,5S)-5-{2-[(1R)- 1-hydroxyethyl]-1H- imidazo[4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <500 | n/a | n/a | n/a | n/a | n/a | 25 |
Incyte Corporation US Patent | Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ... | US Patent US10053465 (2018) BindingDB Entry DOI: 10.7270/Q2B27X98 | |||||||||||
More data for this Ligand-Target Pair |