Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50384588'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50384588 (CHEMBL2036624 | US9744172, Compound UNC00000270A) Show SMILES CNc1ncc2c(nn(CC3CCNCC3)c2n1)C(C)C Show InChI InChI=1S/C15H24N6/c1-10(2)13-12-8-18-15(16-3)19-14(12)21(20-13)9-11-4-6-17-7-5-11/h8,10-11,17H,4-7,9H2,1-3H3,(H,16,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...				ACS Med Chem Lett 3: 129-134 (2012) Article DOI: 10.1021/ml200239k BindingDB Entry DOI: 10.7270/Q2F76DMC
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50384588 (CHEMBL2036624 | US9744172, Compound UNC00000270A) Show SMILES CNc1ncc2c(nn(CC3CCNCC3)c2n1)C(C)C Show InChI InChI=1S/C15H24N6/c1-10(2)13-12-8-18-15(16-3)19-14(12)21(20-13)9-11-4-6-17-7-5-11/h8,10-11,17H,4-7,9H2,1-3H3,(H,16,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...				US Patent US9744172 (2017) BindingDB Entry DOI: 10.7270/Q2PR7Z30
					More data for this Ligand-Target Pair