Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50444085'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444085 (CHEMBL3092785 | US9649309, Compound UNC1917A) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccccn1 |r,wU:11.10,wD:14.14,(15.34,-10.98,;16.67,-10.21,;18,-10.98,;19.34,-10.21,;20.67,-10.98,;22,-10.22,;23.34,-10.99,;24.68,-10.21,;24.67,-8.66,;23.33,-7.9,;23.33,-6.36,;21.99,-5.59,;20.67,-6.37,;19.33,-5.59,;19.33,-4.05,;18,-3.28,;20.67,-3.28,;21.99,-4.05,;22.01,-8.67,;26,-7.89,;27.33,-8.66,;28.66,-7.89,;28.66,-6.34,;27.31,-5.58,;25.99,-6.36,)| Show InChI InChI=1S/C19H27N5O/c1-2-3-11-21-19-22-13-16(17-6-4-5-12-20-17)18(24-19)23-14-7-9-15(25)10-8-14/h4-6,12-15,25H,2-3,7-11H2,1H3,(H2,21,22,23,24)/t14-,15-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444085 (CHEMBL3092785 | US9649309, Compound UNC1917A) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccccn1 |r,wU:11.10,wD:14.14,(15.34,-10.98,;16.67,-10.21,;18,-10.98,;19.34,-10.21,;20.67,-10.98,;22,-10.22,;23.34,-10.99,;24.68,-10.21,;24.67,-8.66,;23.33,-7.9,;23.33,-6.36,;21.99,-5.59,;20.67,-6.37,;19.33,-5.59,;19.33,-4.05,;18,-3.28,;20.67,-3.28,;21.99,-4.05,;22.01,-8.67,;26,-7.89,;27.33,-8.66,;28.66,-7.89,;28.66,-6.34,;27.31,-5.58,;25.99,-6.36,)| Show InChI InChI=1S/C19H27N5O/c1-2-3-11-21-19-22-13-16(17-6-4-5-12-20-17)18(24-19)23-14-7-9-15(25)10-8-14/h4-6,12-15,25H,2-3,7-11H2,1H3,(H2,21,22,23,24)/t14-,15-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...				US Patent US9649309 (2017) BindingDB Entry DOI: 10.7270/Q26Q209H
					More data for this Ligand-Target Pair				3D Structure (crystal)