Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50444248'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444248 (CHEMBL3093749) Show SMILES CCCCNc1ncc(C(=O)Nc2cccc(OC)c2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:22.22,wD:25.26,(37.13,-46.79,;38.46,-46.02,;39.8,-46.79,;41.13,-46.02,;42.46,-46.79,;43.8,-46.02,;45.13,-46.79,;46.47,-46.02,;46.46,-44.47,;47.79,-43.7,;47.79,-42.16,;49.13,-44.46,;50.46,-43.69,;50.45,-42.16,;51.77,-41.38,;53.12,-42.14,;53.12,-43.68,;54.46,-44.45,;55.79,-43.68,;51.79,-44.46,;45.13,-43.71,;45.12,-42.17,;43.79,-41.4,;42.45,-42.18,;41.12,-41.41,;41.12,-39.87,;39.78,-39.1,;42.45,-39.1,;43.78,-39.86,;43.8,-44.48,)| Show InChI InChI=1S/C22H31N5O3/c1-3-4-12-23-22-24-14-19(20(27-22)25-15-8-10-17(28)11-9-15)21(29)26-16-6-5-7-18(13-16)30-2/h5-7,13-15,17,28H,3-4,8-12H2,1-2H3,(H,26,29)(H2,23,24,25,27)/t15-,17-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Eshelman School of Pharmacy�Department of Pharmacology�Lineberger Compreh Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9693-700 (2014) Article DOI: 10.1021/jm4013888 BindingDB Entry DOI: 10.7270/Q21G0NQ1
					More data for this Ligand-Target Pair