Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM196798'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM196798 (US9212178, 27) Show SMILES Cc1nn(cc1CN1C[C@H](O)CO1)-c1ccnc(Nc2ccc3n(cc(C(=O)C4CC4)c3c2)S(C)(=O)=O)n1 |r| Show InChI InChI=1S/C25H27N7O5S/c1-15-17(10-30-12-19(33)14-37-30)11-31(29-15)23-7-8-26-25(28-23)27-18-5-6-22-20(9-18)21(24(34)16-3-4-16)13-32(22)38(2,35)36/h5-9,11,13,16,19,33H,3-4,10,12,14H2,1-2H3,(H,26,27,28)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.89	n/a	n/a	n/a	n/a	n/a	25
Genosco; Oscotec, Inc. US Patent					Assay Description Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...				US Patent US9212178 (2015) BindingDB Entry DOI: 10.7270/Q2X9294C
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