Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM256547'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM256547 (US10435361, Example 46 | US9481648, 46 | US9790174...) Show SMILES COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(cc(C(=O)NCCN(C)C)c4OC)C(C)(C)C)c4ccccc34)n2)cc(OC)c1 Show InChI InChI=1S/C45H57N7O9/c1-45(2,3)30-25-36(42(53)46-17-18-52(4)5)41(57-8)38(26-30)50-44(54)49-37-13-14-39(35-12-10-9-11-34(35)37)61-40-15-16-47-43(51-40)48-31-27-32(56-7)29-33(28-31)60-24-23-59-22-21-58-20-19-55-6/h9-16,25-29H,17-24H2,1-8H3,(H,46,53)(H,47,48,51)(H2,49,50,54)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Limited; Topivert Pharma Limited US Patent					Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...				US Patent US9790174 (2017) BindingDB Entry DOI: 10.7270/Q2M61NCF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM256547 (US10435361, Example 46 | US9481648, 46 | US9790174...) Show SMILES COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(cc(C(=O)NCCN(C)C)c4OC)C(C)(C)C)c4ccccc34)n2)cc(OC)c1 Show InChI InChI=1S/C45H57N7O9/c1-45(2,3)30-25-36(42(53)46-17-18-52(4)5)41(57-8)38(26-30)50-44(54)49-37-13-14-39(35-12-10-9-11-34(35)37)61-40-15-16-47-43(51-40)48-31-27-32(56-7)29-33(28-31)60-24-23-59-22-21-58-20-19-55-6/h9-16,25-29H,17-24H2,1-8H3,(H,46,53)(H,47,48,51)(H2,49,50,54)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Limited; Topivert Pharma Limited US Patent					Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...				US Patent US9481648 (2016) BindingDB Entry DOI: 10.7270/Q24F1PNH
					More data for this Ligand-Target Pair