Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM260705'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM260705 (US9533989, 15) Show SMILES N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2ccc3CCN(Cc3c2)C(=O)C2CCC2)n1 Show InChI InChI=1S/C25H33N7O2/c26-20-6-1-2-7-21(20)30-25-28-13-19(22(27)33)23(31-25)29-18-9-8-15-10-11-32(14-17(15)12-18)24(34)16-4-3-5-16/h8-9,12-13,16,20-21H,1-7,10-11,14,26H2,(H2,27,33)(H2,28,29,30,31)/t20-,21+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.96	n/a	n/a	n/a	n/a	n/a	n/a
Ziarco Pharma Ltd. US Patent					Assay Description The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...				US Patent US9533989 (2017) BindingDB Entry DOI: 10.7270/Q2VQ31M7
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