Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM290761'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM290761 (2-((1R,2S)-2- aminocyclohexylamino)- 4-(quinolin-6...) Show SMILES N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2ccc3ncccc3c2)n1 |r| Show InChI InChI=1S/C20H23N7O/c21-15-5-1-2-6-17(15)26-20-24-11-14(18(22)28)19(27-20)25-13-7-8-16-12(10-13)4-3-9-23-16/h3-4,7-11,15,17H,1-2,5-6,21H2,(H2,22,28)(H2,24,25,26,27)/t15-,17+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	7.5	25
Portola Pharmaceuticals, Inc. US Patent					Assay Description Potency of candidate molecules for inhibiting syk tyrosine phosphorylation activity is assessed by measuring the ability of a test compound to inhibi...				US Patent US9579320 (2017) BindingDB Entry DOI: 10.7270/Q2K07692
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