Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM322683'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM322683 (2-(azepan-1-yl)-4-((4-(piperazin-1- ylmethyl)pheny...) Show SMILES O=c1[nH]ncc2nc(nc(Nc3ccc(CN4CCNCC4)cc3)c12)N1CCCCCC1 Show InChI InChI=1S/C23H30N8O/c32-22-20-19(15-25-29-22)27-23(31-11-3-1-2-4-12-31)28-21(20)26-18-7-5-17(6-8-18)16-30-13-9-24-10-14-30/h5-8,15,24H,1-4,9-14,16H2,(H,29,32)(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Asan BioSciences, LLC US Patent					Assay Description 2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...				US Patent US10647720 (2020) BindingDB Entry DOI: 10.7270/Q2QJ7MB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM322683 (2-(azepan-1-yl)-4-((4-(piperazin-1- ylmethyl)pheny...) Show SMILES O=c1[nH]ncc2nc(nc(Nc3ccc(CN4CCNCC4)cc3)c12)N1CCCCCC1 Show InChI InChI=1S/C23H30N8O/c32-22-20-19(15-25-29-22)27-23(31-11-3-1-2-4-12-31)28-21(20)26-18-7-5-17(6-8-18)16-30-13-9-24-10-14-30/h5-8,15,24H,1-4,9-14,16H2,(H,29,32)(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Asana BioSciences, LLC US Patent					Assay Description 2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...				US Patent US10183944 (2019) BindingDB Entry DOI: 10.7270/Q2BC41MH
					More data for this Ligand-Target Pair