Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM322905'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM322905 (2-(azepan-1-yl)-4-((4-(4-(2-fluoroethyl) piperazin...) Show SMILES FCCN1CCN(CC1)c1ccc(Nc2nc(nc3cn[nH]c(=O)c23)N2CCCCCC2)cc1 Show InChI InChI=1S/C24H31FN8O/c25-9-12-31-13-15-32(16-14-31)19-7-5-18(6-8-19)27-22-21-20(17-26-30-23(21)34)28-24(29-22)33-10-3-1-2-4-11-33/h5-8,17H,1-4,9-16H2,(H,30,34)(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Asan BioSciences, LLC US Patent					Assay Description 2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...				US Patent US10647720 (2020) BindingDB Entry DOI: 10.7270/Q2QJ7MB7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM322905 (2-(azepan-1-yl)-4-((4-(4-(2-fluoroethyl) piperazin...) Show SMILES FCCN1CCN(CC1)c1ccc(Nc2nc(nc3cn[nH]c(=O)c23)N2CCCCCC2)cc1 Show InChI InChI=1S/C24H31FN8O/c25-9-12-31-13-15-32(16-14-31)19-7-5-18(6-8-19)27-22-21-20(17-26-30-23(21)34)28-24(29-22)33-10-3-1-2-4-11-33/h5-8,17H,1-4,9-16H2,(H,30,34)(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Asana BioSciences, LLC US Patent					Assay Description 2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...				US Patent US10183944 (2019) BindingDB Entry DOI: 10.7270/Q2BC41MH
					More data for this Ligand-Target Pair