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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM334346'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM334346
PNG
(1-(4-((2-((3-(2,5,8,11,14-Pentaoxahexadecan-16-ylo...)
Show SMILES COCCOCCOCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C(C)C)c4ccccc34)n2)cc(OC)c1
Show InChI InChI=1S/C46H55N7O9/c1-32(2)41-31-43(53(52-41)35-12-10-33(3)11-13-35)50-46(54)49-40-14-15-42(39-9-7-6-8-38(39)40)62-44-16-17-47-45(51-44)48-34-28-36(56-5)30-37(29-34)61-27-26-60-25-24-59-23-22-58-21-20-57-19-18-55-4/h6-17,28-32H,18-27H2,1-5H3,(H,47,48,51)(H2,49,50,54)
PDB
MMDB

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PC cid
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US Patent
n/an/a 12n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...


US Patent US9732063 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6NGV
More data for this
Ligand-Target Pair