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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM342109'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM342109
PNG
(3-((4-((4-(3-(3-(tert-Butyl)-1-methyl-1H-pyrazol-5...)
Show SMILES COCCOCCOCCNC(=O)c1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(nn4C)C(C)(C)C)c4ccccc34)ccn2)cc(c1)C#C
Show InChI InChI=1S/C40H45N7O6/c1-7-27-22-28(38(48)42-16-17-51-20-21-52-19-18-50-6)24-29(23-27)43-36-25-30(14-15-41-36)53-34-13-12-33(31-10-8-9-11-32(31)34)44-39(49)45-37-26-35(40(2,3)4)46-47(37)5/h1,8-15,22-26H,16-21H2,2-6H3,(H,41,43)(H,42,48)(H2,44,45,49)
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US Patent
n/an/a>1.00E+3n/an/an/an/an/an/a



TOPIVERT PHARMA LIMITED; RESPIVERT LIMITED

US Patent


Assay Description
GSK 3α: The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determinin...

US Patent US9771353 (2017)


BindingDB Entry DOI: 10.7270/Q2HQ4219
More data for this
Ligand-Target Pair