Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50126437'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126437 (CHEMBL30826 | N*1*-[7-(4-Dimethylamino-phenyl)-[1,...) Show SMILES CN(C)c1ccc(cc1)-c1cc2ncccc2c(NCCN)n1 Show InChI InChI=1S/C18H21N5/c1-23(2)14-7-5-13(6-8-14)16-12-17-15(4-3-10-20-17)18(22-16)21-11-9-19/h3-8,10,12H,9,11,19H2,1-2H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against spleen tyrosine kinase (SYK)				Bioorg Med Chem Lett 13: 1415-8 (2003) BindingDB Entry DOI: 10.7270/Q2MC8ZCJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126437 (CHEMBL30826 | N*1*-[7-(4-Dimethylamino-phenyl)-[1,...) Show SMILES CN(C)c1ccc(cc1)-c1cc2ncccc2c(NCCN)n1 Show InChI InChI=1S/C18H21N5/c1-23(2)14-7-5-13(6-8-14)16-12-17-15(4-3-10-20-17)18(22-16)21-11-9-19/h3-8,10,12H,9,11,19H2,1-2H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Rigel, Inc. Curated by ChEMBL					Assay Description Inhibition of SYK				J Med Chem 55: 3614-43 (2012) Article DOI: 10.1021/jm201271b BindingDB Entry DOI: 10.7270/Q2NZ88RC
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50126437 (CHEMBL30826 | N*1*-[7-(4-Dimethylamino-phenyl)-[1,...) Show SMILES CN(C)c1ccc(cc1)-c1cc2ncccc2c(NCCN)n1 Show InChI InChI=1S/C18H21N5/c1-23(2)14-7-5-13(6-8-14)16-12-17-15(4-3-10-20-17)18(22-16)21-11-9-19/h3-8,10,12H,9,11,19H2,1-2H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant Syk (unknown origin)				Bioorg Med Chem Lett 19: 1944-9 (2009) Article DOI: 10.1016/j.bmcl.2009.02.049 BindingDB Entry DOI: 10.7270/Q2WM1D98
					More data for this Ligand-Target Pair