Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50400041'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50400041 (CHEMBL2177729) Show SMILES COc1ccc(Nc2nc(nc3scnc23)N2CCCC(C2)NC(=O)c2ccc(cc2)C(O)=O)cc1OC Show InChI InChI=1S/C26H26N6O5S/c1-36-19-10-9-17(12-20(19)37-2)28-22-21-24(38-14-27-21)31-26(30-22)32-11-3-4-18(13-32)29-23(33)15-5-7-16(8-6-15)25(34)35/h5-10,12,14,18H,3-4,11,13H2,1-2H3,(H,29,33)(H,34,35)(H,28,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	423	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysis				J Med Chem 55: 10414-23 (2012) Article DOI: 10.1021/jm301367c BindingDB Entry DOI: 10.7270/Q2057H23
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