Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase TXK' and Ligand = 'BDBM434523'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434523 (US10562893, Compound 19) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3cccnc3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C29H32N6O2/c1-6-26(36)32-22-10-7-11-23(16-22)35-25-13-12-20(17-31-19(2)29(3,4)5)15-24(25)33-28(35)34-27(37)21-9-8-14-30-18-21/h6-16,18-19,31H,1,17H2,2-5H3,(H,32,36)(H,33,34,37)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
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