Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Yes (Homo sapiens (Human)) | BDBM50306684 (2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co, Ltd Curated by ChEMBL | Assay Description Inhibition of recombinant YES by TR-FRET assay | Bioorg Med Chem Lett 20: 1405-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.109 BindingDB Entry DOI: 10.7270/Q2HQ401G | |||||||||||
More data for this Ligand-Target Pair |