Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ZAP-70' and Ligand = 'BDBM26419'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM26419 (7-[(3,5-dimethoxyphenyl)amino]-5-{[(4-sulfamoylphe...) Show SMILES COc1cc(Nc2nc(NCc3ccc(cc3)S(N)(=O)=O)n3ccnc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C22H23N7O5S/c1-33-15-9-14(10-16(11-15)34-2)27-20-18(19(23)30)21-25-7-8-29(21)22(28-20)26-12-13-3-5-17(6-4-13)35(24,31)32/h3-11,27H,12H2,1-2H3,(H2,23,30)(H,26,28)(H2,24,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	7.6	30
Kissei Pharmaceutical Company					Assay Description A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...				Bioorg Med Chem 17: 284-94 (2009) Article DOI: 10.1016/j.bmc.2008.10.070 BindingDB Entry DOI: 10.7270/Q2FQ9TXB
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