Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase receptor' and Ligand = 'BDBM144313'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor (Homo sapiens (Human))	BDBM144313 (US8969336, 545) Show SMILES CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)CC2)nc1NC1CCOCC1 Show InChI InChI=1S/C23H33N7O2/c1-3-19-22(25-17-8-14-32-15-9-17)28-23(20(27-19)21(24)31)26-16-4-6-18(7-5-16)30-12-10-29(2)11-13-30/h4-7,17H,3,8-15H2,1-2H3,(H2,24,31)(H2,25,26,28)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; Kotobuki Pharmaceutical Co., Ltd. US Patent					Assay Description A recombinant retrovirus was created from expression plasmid FLAG-EML4-ALKv1/pMX-iresCD8 in which cDNA for EMLA-ALK fusion protein v1 was integrated,...				US Patent US8969336 (2015) BindingDB Entry DOI: 10.7270/Q2NV9GZW
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