Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1' and Ligand = 'BDBM50072594'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50072594 (CHEMBL114030 | Sodium; biphenyl-3-yl-difluoro-acet...) Show SMILES [O-]C(=O)C(F)(F)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C14H10F2O2/c15-14(16,13(17)18)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9H,(H,17,18)/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate as substrate at Km concentration (20 uM)				Bioorg Med Chem Lett 8: 3275-80 (1999) BindingDB Entry DOI: 10.7270/Q20R9NK3
					More data for this Ligand-Target Pair