Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1' and Ligand = 'BDBM50224548'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50224548 (2-(5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)e...) Show SMILES Cc1nc(sc1CCOc1ccc2n(COCC[Si](C)(C)C)cc(c2c1)C(O)(C(O)=O)C(F)(F)F)-c1ccc(Cl)cc1 |w:26.29| Show InChI InChI=1S/C29H32ClF3N2O5SSi/c1-18-25(41-26(34-18)19-5-7-20(30)8-6-19)11-12-40-21-9-10-24-22(15-21)23(28(38,27(36)37)29(31,32)33)16-35(24)17-39-13-14-42(2,3)4/h5-10,15-16,38H,11-14,17H2,1-4H3,(H,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Heriot-Watt University Curated by ChEMBL					Assay Description Inhibition of PTP1B expressed in Sf9 cells				Bioorg Med Chem Lett 17: 6579-83 (2007) Article DOI: 10.1016/j.bmcl.2007.09.069 BindingDB Entry DOI: 10.7270/Q2W37W1K
					More data for this Ligand-Target Pair