Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50268461 (CHEMBL4098715) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
School of Life Science, Biotechnology, Dalian University of Technology, Dalian, Liaoning 116024, China. Curated by ChEMBL | Assay Description Competitive inhibition of PTP1B (unknown origin) at 0.1 to 0.4 uM using p-nitrophenyl phosphate substrate incubated for 30 mins by Lineweaver-Burk do... | Bioorg Med Chem Lett 27: 3382-3385 (2017) Article DOI: 10.1016/j.bmcl.2017.06.001 BindingDB Entry DOI: 10.7270/Q2G1639V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50268461 (CHEMBL4098715) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Life Science, Biotechnology, Dalian University of Technology, Dalian, Liaoning 116024, China. Curated by ChEMBL | Assay Description Inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate substrate incubated for 30 mins | Bioorg Med Chem Lett 27: 3382-3385 (2017) Article DOI: 10.1016/j.bmcl.2017.06.001 BindingDB Entry DOI: 10.7270/Q2G1639V | |||||||||||
More data for this Ligand-Target Pair |