Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM433292'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM433292 (6-amino-2-(3- (aminomethyl)-3- methylpyrrolidin-1-...) Show SMILES Cn1c(nc(N)c(Sc2cccc(Cl)c2Cl)c1=O)N1CCC(C)(CN)C1 Show InChI InChI=1S/C17H21Cl2N5OS/c1-17(8-20)6-7-24(9-17)16-22-14(21)13(15(25)23(16)2)26-11-5-3-4-10(18)12(11)19/h3-5H,6-9,20-21H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYNBLia Therapeutics, Inc. US Patent					Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...				US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z
					More data for this Ligand-Target Pair