Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM446457'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM446457 ((R)-1-((7-cyano-2-(3′-(7-(((S)-2-hydroxyprop...) Show SMILES C[C@H](O)CNCc1cnc2c(Nc3cccc(c3C)-c3cccc(-c4nc5cc(CN6CC[C@H](C6)C(O)=O)cc(C#N)c5o4)c3C)nc(C)nc2c1 |r| Show InChI InChI=1S/C40H40N8O4/c1-22(49)17-42-18-27-15-34-36(43-19-27)38(45-25(4)44-34)46-33-10-6-8-31(24(33)3)30-7-5-9-32(23(30)2)39-47-35-14-26(13-29(16-41)37(35)52-39)20-48-12-11-28(21-48)40(50)51/h5-10,13-15,19,22,28,42,49H,11-12,17-18,20-21H2,1-4H3,(H,50,51)(H,44,45,46)/t22-,28+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description U2OS/PD-L1 cells (DiscoveRx Corporation) were maintained in McCoy's 5A medium with addition of 10% FBS, 0.25 μg/ml Puromycin. After removing...				US Patent US10669271 (2020) BindingDB Entry DOI: 10.7270/Q2MG7SJC
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