Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosyl-DNA phosphodiesterase 1' and Ligand = 'BDBM50067506'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50067506 (CHEMBL3401898) Show SMILES FC(F)(F)c1cc(NC(=O)CCN2CCCCC2)c2SSSSSc2c1 Show InChI InChI=1S/C15H17F3N2OS5/c16-15(17,18)10-8-11(14-12(9-10)22-24-26-25-23-14)19-13(21)4-7-20-5-2-1-3-6-20/h8-9H,1-7H2,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant TDP1 (unknown origin) assessed as increase in fluorescence				Bioorg Med Chem 23: 2044-52 (2015) Article DOI: 10.1016/j.bmc.2015.03.020 BindingDB Entry DOI: 10.7270/Q2ZW1NMK
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