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Found 1 hit Enz. Inhib. hit(s) with Target = 'U5 small nuclear ribonucleoprotein 200 kDa helicase' and Ligand = 'BDBM50260431'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
U5 small nuclear ribonucleoprotein 200 kDa helicase


(Homo sapiens (Human))		BDBM50260431
PNG
(CHEMBL4076160)
Show SMILES CC(C)C[C@H]1C[C@@H](C(N)=O)[C@@]2(N1C(=O)c1ccccn1)C(=O)Nc1ccccc21 |r|
Show InChI InChI=1S/C22H24N4O3/c1-13(2)11-14-12-16(19(23)27)22(15-7-3-4-8-17(15)25-21(22)29)26(14)20(28)18-9-5-6-10-24-18/h3-10,13-14,16H,11-12H2,1-2H3,(H2,23,27)(H,25,29)/t14-,16-,22+/m0/s1
PDB
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

Curated by ChEMBL


Assay Description
Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...

Bioorg Med Chem 25: 4753-4767 (2017)


Article DOI: 10.1016/j.bmc.2017.07.017
BindingDB Entry DOI: 10.7270/Q27M0BDH
More data for this
Ligand-Target Pair