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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'UL37 immediate early glycoprotein' and Ligand = 'BDBM435736'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
UL37 immediate early glycoprotein


(HHV-5)		BDBM435736
PNG
(US10610539, Compound mannose)
Show SMILES CC1OC(CC(OC2OC(CO)[C@H](O)C(O)[C@@H]2O)C1C)OC1C(O)CC(OC2C(O)CC(O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4CC[C@]4(C)[C@H](CC[C@]54O)C4=CC(=O)OC4)C3)OC2C)OC1C |r,t:57|
Show InChI InChI=1S/C48H76O17/c1-22-23(2)58-39(19-34(22)62-45-42(55)41(54)40(53)35(20-49)63-45)65-44-25(4)60-38(18-33(44)51)64-43-24(3)59-37(17-32(43)50)61-28-9-12-46(5)27(16-28)7-8-31-30(46)10-13-47(6)29(11-14-48(31,47)56)26-15-36(52)57-21-26/h15,22-25,27-35,37-45,49-51,53-56H,7-14,16-21H2,1-6H3/t22?,23?,24?,25?,27-,28+,29-,30+,31-,32?,33?,34?,35?,37?,38?,39?,40+,41?,42+,43?,44?,45?,46+,47-,48+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 7.31n/an/an/an/a



The John Hopkins University

US Patent


Assay Description
The effect of digitoxin analogs on HCMV replication was tested. HFFs were infected with pp28-luciferase HCMV and treated with the compounds (Table 2,...

US Patent US10610539 (2020)


BindingDB Entry DOI: 10.7270/Q27084F9
More data for this
Ligand-Target Pair