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Found 1 hit Enz. Inhib. hit(s) with Target = 'Uracil-DNA glycosylase' and Ligand = 'BDBM50343396'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343396
PNG
(CHEMBL1551959 | ethyl 4-(4-(dimethylamino)phenylam...)
Show SMILES CCOC(=O)c1cnc2c(ccc3ccccc23)c1Nc1ccc(cc1)N(C)C
Show InChI InChI=1S/C24H23N3O2/c1-4-29-24(28)21-15-25-22-19-8-6-5-7-16(19)9-14-20(22)23(21)26-17-10-12-18(13-11-17)27(2)3/h5-15H,4H2,1-3H3,(H,25,26)
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.39E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair