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Found 1 hit Enz. Inhib. hit(s) with Target = 'Uracil-DNA glycosylase' and Ligand = 'BDBM50343405'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343405
PNG
(6-(9-chloro-4-(4-fluorophenyl)-5H-chromeno[4,3-b]p...)
Show SMILES OC1COc2ccc(cc2N1)-c1cc(-c2ccc(F)cc2)c2COc3ccc(Cl)cc3-c2n1
Show InChI InChI=1S/C26H18ClFN2O3/c27-16-4-8-23-19(10-16)26-20(12-32-23)18(14-1-5-17(28)6-2-14)11-21(30-26)15-3-7-24-22(9-15)29-25(31)13-33-24/h1-11,25,29,31H,12-13H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair