Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Urokinase-type plasminogen activator' and Ligand = 'BDBM50500937'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50500937 (CHEMBL3800401) Show SMILES CC(C)C[C@@H](N1C(=O)CN(C1=O)c1ccc(Oc2ccccc2)cc1)c1nc2ccc(cc2n1C)C(=O)N[C@@H](CCCCN)C#N |r| Show InChI InChI=1S/C35H39N7O4/c1-23(2)19-31(33-39-29-17-12-24(20-30(29)40(33)3)34(44)38-25(21-37)9-7-8-18-36)42-32(43)22-41(35(42)45)26-13-15-28(16-14-26)46-27-10-5-4-6-11-27/h4-6,10-17,20,23,25,31H,7-9,18-19,22,36H2,1-3H3,(H,38,44)/t25-,31+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hiroshima International University Curated by ChEMBL					Assay Description Inhibition of human urokinase using Pyr-Gly-Arg-MCA as substrate by fluorescence assay				Bioorg Med Chem Lett 26: 2259-61 (2016) Article DOI: 10.1016/j.bmcl.2016.03.047 BindingDB Entry DOI: 10.7270/Q2MK6GX7
					More data for this Ligand-Target Pair