BindingDB PrimarySearch

Found 4 hits Enz. Inhib. hit(s) with Target = 'Urokinase-type plasminogen activator' and Ligand = 'BDBM50529246'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50529246 (CHEMBL4473654) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	302	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of human kidney uPA using fluorogenic Z-Pyr-Gly-Arg-MCA as substrate measured after 15 mins by fluorometric analysis				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126753 BindingDB Entry DOI: 10.7270/Q2BV7M3S
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50529246 (CHEMBL4473654) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of human kidney uPA using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrate				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126753 BindingDB Entry DOI: 10.7270/Q2BV7M3S
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50529246 (CHEMBL4473654) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of human uPA				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126753 BindingDB Entry DOI: 10.7270/Q2BV7M3S
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase-type plasminogen activator (Mus musculus (Mouse))	BDBM50529246 (CHEMBL4473654) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of mouse uPA				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126753 BindingDB Entry DOI: 10.7270/Q2BV7M3S
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair