BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Urotensin-2 receptor' and Ligand = 'BDBM50252039'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urotensin-2 receptor


(Homo sapiens (Human))		BDBM50252039
PNG
((S)-N-(1-(3-(3-(dimethylamino)propoxy)benzyl)pyrro...)
Show SMILES CN(C)CCCOc1cccc(CN2CC[C@@H](C2)NC(=O)c2ccc(Cl)c(Cl)c2)c1 |r|
Show InChI InChI=1S/C23H29Cl2N3O2/c1-27(2)10-4-12-30-20-6-3-5-17(13-20)15-28-11-9-19(16-28)26-23(29)18-7-8-21(24)22(25)14-18/h3,5-8,13-14,19H,4,9-12,15-16H2,1-2H3,(H,26,29)/t19-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>3.00E+3n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...

Bioorg Med Chem Lett 18: 3950-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.019
BindingDB Entry DOI: 10.7270/Q2FT8KTR
More data for this
Ligand-Target Pair